Peripheral Artery Disease (PAD) is a common, progressive circulatory problem that affects more than 20 million people in the U.S. and over 202 million people globally.1, 2
PAD develops when arteries become clogged with plaque that limits blood flow to the leg. The blockage can cause poor circulation, pain while walking, and changes in skin color.
PAD often advances to critical limb ischemia (CLI), the most severe form of the disease. CLI symptoms significantly increase in severity: pain when resting, open sores, and/or life-threatening conditions such as infection and gangrene. Left untreated, 50% of patients with CLI will undergo an amputation or die within the first year.3